As much as I love my neighborhood during the day, I stay as far away as I possibly can when the frat boys come out to drink on Saturday nights. Pharmacy Bar is less maddening, and almost peaceful, compared to its neighbors which makes it a great place for pre or post dinner/other plans. The drinks aren't anything fancy or exciting, but they work just fine, and the low key vibe makes it easy to catch up and have a conversation with people.
I gravitate towards places with a good jukebox selection, and this one does! The owner is clearly sending out a message with the music options which cover The Beatles, Bowie, Stones and Elvis; which keep folks who love Pitbull far away. If the jukebox isn't your thing, go check out their old school video games. They have Pacman, which is surprisingly still fun.
And finally, if none of these options keep you entertained - grab a seat by the bay windows. I can almost guarantee that watching drunk kids hobble down 18th street will keep you amused for a long time.